miR-126 Is Involved in Vascular Remodeling under Laminar Shear Stress

Figure 3

LSS increases KLF-2 mRNA expression and regulates miRNA expression in HUVECs. HUVECs cells were exposed to various durations of laminar shear stress (10 min and 24 h). (a) LSS increased KLF-2 mRNA expression. Values are expressed as mean ± SD of 3 experiments. (b) 24 h of LSS increased miR-126 levels in HUVECs. Values are expressed as mean ± SD of 3 independent experiments (AU: arbitrary units). Student’s -test, for KLF-2: (10 min of LSS versus static), (24 h of LSS versus static); for miR-126: (10 min of LSS versus static), (24 h of LSS versus static).

(a)

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