Cardamonin Regulates miR-21 Expression and Suppresses Angiogenesis Induced by Vascular Endothelial Growth Factor

Figure 3

Cardamonin-mediated inhibition of HUVECs migration. Note: HUVECs in a six-well plate were photographed at the 0 h and 24 h time points. The areas of cells that migrated to the wound zones were measured separately with Image-Pro Plus 6.0 software. The experiment was repeated 3 times. (a) Cells in a six-well plate were photographed at 24 h time points. (b) The areas of cells that migrated into the wound zones, after treated with VEGF (control), VEGF + miR-21s, VEGF + cardamonin, or VEGF + cardamonin + miR-21s. as compared with the VEGF group, and 0.01, respectively, as compared with the VEGF+ cardamonin group.

(a)

(b)