Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells into Insulin-Producing Cells: Evidence for Further Maturation In Vivo

Figure 3

The percentage of insulin-positive cells before transplantation and 1, 2, 4, and 12 weeks after transplantation. Compared to the pretransplantation values, the mean percentage of IPCs (insulin-producing cells) was significantly increased by one week after transplantation. The percentage of IPCs increased progressively, peaking at 4 weeks (18.04 ± 3.3%). There was no substantial change in the percentage of IPCs thereafter.