Differential Regulation of MicroRNAs in End-Stage Failing Hearts Is Associated with Left Ventricular Assist Device Unloading

Figure 1

Clinical parameters of individual patients. (a) CI: cardiac index (off-pump); (b) PCWP: pulmonary capillary wedge pressure; (c) LVEF: left ventricular ejection fraction; (d) LVESV: left ventricular end-systolic volume; (e) LVEDV: left ventricular end-diastolic volume; (f) LVEDD: left ventricular end-diastolic diameter; (g) PASP: pulmonary artery systolic pressure; (h) PADP: pulmonary artery diastolic pressure; (i) NT-proBNP: N-terminal prohormone of brain natriuretic peptide. For patients belonging to HTx-LVAD group, available measurements before implantation of assistance device (pre-LVAD) and before heart transplant (post-LVAD) are shown. Statistical significance is calculated according to Student’s -test (; ; ). In the HTx-LVAD group, paired -test is used to compare pre-LVAD and post-LVAD values.

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