Differential Regulation of MicroRNAs in End-Stage Failing Hearts Is Associated with Left Ventricular Assist Device Unloading

Figure 2

Sample clustering based on sequenced microRNA profiles. Variance-stabilizing transformed count data was used for all samples. The heat map shows a greyscale false colour representation of the Euclidean distance matrix, and the dendrogram represents a hierarchical clustering. Separately, HTx-CTRL and HTx-LVAD samples show a good degree of similarity and group together with the exception of HTx-LVAD (3) and HTx-CTRL (2), which were excluded from downstream analysis.