Temozolomide and Radiotherapy versus Radiotherapy Alone in High Grade Gliomas: A Very Long Term Comparative Study and Literature Review

Table 1

Group A and group B: patients’ characteristics.

	Group A	Group B
Patients’ number	31	33
Age
Range	41–78 years	26–74 years
Median	62 years	57 years
Sex
Male	17 pts	18 pts
Female	14 pts	15 pts
Karnofsky Index
Range	60–90	60–90
Medium	70	70
Surgery
Stereotactic biopsy	3 pts	9 pts
Subtotal resection	18 pts	12 pts
Total resection	10 pts	12 pts
Histology
Anaplastic astrocytoma	11 pts	10 pts
Glioblastoma multiforme	20 pts	23 pts
RT total dose
Median	64 Gy	63 Gy
Range	45 Gy–66 Gy	45 Gy–64 Gy
<50 Gy	2 pts	1 pts
≥50 Gy <60 Gy	5 pts	2 pts
≥60 Gy	24 pts	30 pts