Temozolomide and Radiotherapy versus Radiotherapy Alone in High Grade Gliomas: A Very Long Term Comparative Study and Literature Review

Table 2

Groups A + B and group C: patients’ characteristics.

	Groups A + B	Group C
Patients’ number	64	64
Age
Range	26–78 years	29–74 years
Median	59 years	60 years
Sex
Male	35 pts	39 pts
Female	29 pts	25 pts
Karnofsky Index
Range	60–90	60–90
Medium	70	70
Surgery
Stereotactic biopsy	12 pts	11 pts
Subtotal resection	30 pts	35 pts
Total resection	22 pts	18 pts
Histology
Anaplastic astrocytoma	21 pts	14 pts
Glioblastoma multiforme	43 pts	50 pts
RT total dose
Median	61 Gy	59 Gy
Range	45 Gy–66 Gy	35 Gy–66 Gy
<50 Gy	3 pts	3 pts
≥50 Gy <60 Gy	7 pts	6 pts
≥60 Gy	54 pts	55 pts