Temozolomide and Radiotherapy versus Radiotherapy Alone in High Grade Gliomas: A Very Long Term Comparative Study and Literature Review

Table 5

Multivariate analysis group A and group B patients.

Prognostic factors
Age
≤55 years–>55 years	0.04
Sex
Male—female	n.s.
Histology
AA—GBM	0.0003
Surgery
Stereotactic Biopsy—subtotal resection—total resection	0.05
Timing TMZ
Adjuvant—concomitant/adjuvant	n.s.
RT total dose
<60 Gy–≥60 Gy	0.0001