Retinal Imaging of Infants on Spectral Domain Optical Coherence Tomography

Figure 3

The centripetal growth of the IS-OS or EZ band from the periphery to the foveal center at different age groups imaged on the same infant (photo courtesy of Figures 3(a)–3(e) from Figures –90.6, Page 259–360, Chapter 90 of [59]).

(a) The IS OS band or EZ first appears as a distinct hyperreflective band that first begins above the RPE band and then converges towards the center from the periphery (centripetal growth). At 38 weeks of PMA, two faint shadows (blue arrows) are seen at the two ends of the image

(b) The same infant imaged 4 weeks later at 42-week PMA, showing a more clearly visible second layer at the periphery (blue arrows)

(c) Four more weeks later at 46-week PMA, the two bands are now seen coming closer to each other towards the foveal center

(d) At 47-week PMA the EZ band from either side appears to almost touch at the foveal center

(e) At 48-week PMA in this case, both ends of the EZ band join at the foveal center and appear as a distinct layer