Cyclic Tensile Strain Induces Tenogenic Differentiation of Tendon-Derived Stem Cells in Bioreactor Culture

Table 2

The top 20 upregulated and downregulated genes with cyclic tensile strain or not.

Fold change	Gene symbol	Gene description
9.32	Tppp3	Tubulin polymerization-promoting protein family member 3
5.38	Rrad	Ras-related associated with diabetes
5.31	Aass	Aminoadipate-semialdehyde synthase
5.2	Elmod1	ELMO/CED-12 domain containing 1
4.88	Crabp2	Cellular retinoic acid binding protein 2
4.65	S100a5	S100 calcium binding protein A5
4.44	Gjb3	Gap junction protein, beta 3
4.2	Kcnn4	Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
3.98	Mthfs	5,10-Methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
3.97	Lmo1	LIM domain only 1
3.83	Cxcl10	Chemokine (C-X-C motif) ligand 10
3.8	S100a10	S100 calcium binding protein A10
3.78	Anxa8	Annexin A8
3.73	Tspan2	Tetraspanin 2
3.68	Ezr	Ezrin
3.66	Crip1	Cysteine-rich protein 1 (intestinal)
3.58	Mlf1ip	Myeloid leukemia factor 1 interacting protein
3.54	Clec2dl1	C-type lectin domain family 2 member D-like 1
3.53	Fam111a	Family with sequence similarity 111, member A
3.38	Atp2b4	ATPase, Ca++ transporting, plasma membrane 4
0.12	IGF-1	Insulin-like growth factor 1
0.14	Stc1	Stanniocalcin 1
0.16	Olr1	Oxidized low density lipoprotein (lectin-like) receptor 1
0.17	Nkd2	Naked cuticle homolog 2 (Drosophila)
0.18	Lpl	Lipoprotein lipase
0.18	Rgs16	Regulator of G-protein signaling 16
0.19	LOC24906	RoBo-1
0.19	Slc15a3	Solute carrier family 15, member 3
0.2	Kbtbd10	Kelch repeat and BTB (POZ) domain containing 10
0.21	Rgs2	Regulator of G-protein signaling 2
0.22	RGD1308023	Similar to CG5521-PA
0.23	RGD1308023	Similar to CG5521-PA
0.23	RGD1308023	Similar to CG5521-PA
0.24	Bmp4	Bone morphogenetic protein 4
0.24	Ibsp	Integrin-binding sialoprotein
0.24	Kcnj2	Potassium inwardly rectifying channel, subfamily J, member 2
0.24	Lmcd1	LIM and cysteine-rich domains 1
0.25	Agtr1a	Angiotensin II receptor, type 1a
0.25	Avpr1a	Arginine vasopressin receptor 1A
0.25	Fat4	FAT tumor suppressor homolog 4 (Drosophila)