Promoting Effects on Proliferation and Chondrogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells by Four “Kidney-Tonifying” Traditional Chinese Herbs
Table 1
Effects of drug-containing serum of Chinese herbal on the cell proliferation of BMSCs determined by MTT.
Drug
OD of experimental group (OD of control group)
OD of blank group
Value of Chinese herbal-enhanced cell proliferation (value of control cell proliferation)
1%
5%
10%
15%
1%
5%
10%
15%
Radix Astragali
5
0.360 ± 0.031
0.379 ± 0.116
0.168 ± 0.046
0.175 ± 0.028
0.063 ± 0.003
0.297 ± 0.034
0.316 ± 0.119
0.105 ± 0.049
0.112 ± 0.031
Salvia
5
0.447 ± 0.036
0.285 ± 0.015
0.273 ± 0.071
0.189 ± 0.068
0.113 ± 0.015
0.334 ± 0.051
0.172 ± 0.030
0.160 ± 0.086
0.076 ± 0.083
Herba Epimedii
5
0.208 ± 0.026
0.243 ± 0.026
0.246 ± 0.046
0.218 ± 0.043
0.089 ± 0.007
0.119 ± 0.033
0.154 ± 0.033
0.157 ± 0.053
0.129 ± 0.050
Saussurea Involucrata
5
0.287 ± 0.149
0.258 ± 0.030
0.329 ± 0.050
0.292 ± 0.072
0.061 ± 0.003
0.226 ± 0.152
0.197 ± 0.033
0.268 ± 0.053
0.231 ± 0.075
Control group
5
0.187 ± 0.002
0.223 ± 0.001
0.263 ± 0.080
0.261 ± 0.070
0.145 ± 0.015
0.042 ± 0.013
0.078 ± 0.016
0.118 ± 0.095
0.116 ± 0.085
Value of Chinese herbal-enhanced cell proliferation = OD of experimental group − OD of blank group; value of control cell proliferation = OD of control group − OD of blank group; comparison between value of Chinese herbal-enhanced cell proliferation and value of control cell proliferation; , .
