Promoting Effects on Proliferation and Chondrogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells by Four “Kidney-Tonifying” Traditional Chinese Herbs
Table 2
Effects of Chinese herbal drug-containing serum on the cell proliferation of TGF-β1-induced BMSCs determined by MTT.
Drug
OD of experimental group (OD of control group)
OD of blank group
Value of Chinese herbal-enhanced cell proliferation (value of control cell proliferation)
1%
5%
10%
15%
1%
5%
10%
15%
Radix Astragali
5
0.390 ± 0.020
0.408 ± 0.001
0.366 ± 0.041
0.528 ± 0.049
0.344 ± 0.051
0.046 ± 0.071
0.064 ± 0.050
0.022 ± 0.092
0.184 ± 0.100
Salvia
5
0.184 ± 0.013
0.194 ± 0.009
0.383 ± 0.011
0.381 ± 0.072
0.134 ± 0.037
0.050 ± 0.05
0.060 ± 0.028
0.249 ± 0.026
0.247 ± 0.109
Herba Epimedii
5
0.243 ± 0.011
0.342 ± 0.025
0.275 ± 0.055
0.279 ± 0.015
0.230 ± 0.036
0.013 ± 0.047
0.112 ± 0.061
0.045 ± 0.091
0.049 ± 0.051
Saussurea Involucrata
5
0.280 ± 0.009
0.358 ± 0.003
0.297 ± 0.061
0.232 ± 0.002
0.229 ± 0.037
0.051 ± 0.046
0.129 ± 0.034
0.068 ± 0.098
0.003 ± 0.035
Control group
5
0.382 ± 0.026
0.380 ± 0.058
0.386 ± 0.006
0.347 ± 0.031
0.346 ± 0.052
0.036 ± 0.036
0.034 ± 0.11
0.040 ± 0.058
0.001 ± 0.083
Value of Chinese herbal-enhanced cell proliferation = OD of experimental group − OD of blank group; value of control cell proliferation = OD of control group − OD of blank group; comparison between value of Chinese herbal-enhanced cell proliferation and value of control cell proliferation; , .