Exercise-Induced Neuroprotection in the Spastic Han Wistar Rat: The Possible Role of Brain-Derived Neurotrophic Factor

Figure 1

BDNF concentration in the cerebellum (a), hippocampus (b), and cortex (c) of rats exposed to sedentary (Sdty), acute (7-day run), or chronic (30-day run) running regimens ( for each treatment in each brain region). The three-way ANOVA revealed no significant three-way or two-way interactions. However, there was a significant effect of treatment duration on BDNF concentration in both cerebellar and cortical regions of acute runners compared with chronically run rats (^** and , resp.). There was a significant effect of running on hippocampal and cortical BDNF levels compared to their sedentary sibling counterparts (^*). Values are mean ± SEM.

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