Resistance Determinants and Their Association with Different Transposons in the Antibiotic-Resistant Streptococcus pneumoniae

Table 2

Antibiotic resistance and transposon genes identified among 138 S. pneumoniae nasopharyngeal isolates from healthy young children.

Serotype (number of strains)	Resistance pattern	Genes detected by PCR		Presumptive transposons
		Resistance genes	Transposon genes	Tn916 family element	Tn5252-like element
23F (16)	Te	tet(M)	int/xis916	Tn916	ICESp23FST81-like
19F (22), 23F (1)	TeC	tet(M), catpC194	int/xis916, intICE	Tn916
6B (10), 14 (1), 19F (2), 23F (4)	ECcTe	tet(M), erm(B)	int/xis916	Tn6002
6B (2), 23F (1)	ECcTe	tet(M), erm(B), mef(E)	int/xis916	Tn2010
6B (1)	ECcTe	tet(M), erm(B), mef(E)	int/xis916, tnpA/tnpR	Tn2017
6B (18), 19F (43), 23A (2), 23F (1)	ECcTeC	tet(M), erm(B), catpC194	int/xis916, int/xisTn5252	Tn6002	Tn5252
6B (1), 19F (5)	ECcTeC	tet(M), erm(B), catpC194	int/xis916, int/xisTn5252, junTn5253	Tn6002	Tn5253-like
6B (1), 19F (3)	ECcTeC	tet(M), erm(B), mef(E), catpC194	int/xis916, int/xisTn5252	Tn2010	Tn5252
6B (2)	ECcTeC	tet(M), erm(B), catpC194	int/xis916, tnpA/tnpR, int/xisTn5252	Tn3872	Tn5252
19F (2)	ECcTeC	tet(M), erm(B), catpC194	int/xis916, intICE	Tn6002	ICESp23FST81-like

E: erythromycin, Cc: clindamycin, Te: tetracycline, and C: chloramphenicol.