The Effect of Bone Marrow-Derived Mesenchymal Stem Cells and Their Conditioned Media Topically Delivered in Fibrin Glue on Chronic Wound Healing in Rats

Table 1

Comparison between the different studied groups according to tensile strength, extension ratio, and healing duration.

	CG	FG	FG + SCs	FG + CM
Tensile strength (Kg/mm^2)	0.015 ± 0.001	0.013 ± 0.003	0.023^ab ± 0.007	0.020^ab ± 0.002	<0.001
Extension ratio (mm)	1.63 ± 0.21	1.65 ± 0.14	2.13^ab ± 0.27	1.99^ab ± 0.21	<0.001
Healing (days)	36.90 ± 4.31	36.30 ± 4.06	34.40 ± 3.66	34.60 ± 4.03	0.426

Data are presented as mean ± SD (tensile strength and extension ratio: /group, healing: /group). One-way ANOVA was conducted and post hoc test for pair comparison. Results are significant at . CG: control group, FG: wound sprayed with fibrin glue, FG + SCs: wound sprayed with MSCs-loaded fibrin glue, and FG + CM: wound sprayed with fibrin glue dissolved in conditioned media. ^aSignificant with CG and ^bsignificant with FG.