Flax Fiber Hydrophobic Extract Inhibits Human Skin Cells Inflammation and Causes Remodeling of Extracellular Matrix and Wound Closure Activation

Figure 8

Expression of genes related to extracellular matrix in NHEK cells after treatments with flax fiber cannabinoid containing extract. Final CBD concentrations 0.211 (Ex 1), 0.105 (Ex 2), and 0.042 (Ex 5) μg/mL; C: untreated cells; EtOH: ethanol-treated cells used as negative control; CBD 1, 2, and 5: positive control samples of pure CBD in concentration corresponding to Ex 1, 2, and 5; SIT1, SIT2, and SIT5: positive control samples of pure β-sitosterol in concentrations corresponding to Ex 1, 2, and 5 (3.63, 1.82, and 0.73 μg/mL). Measurements of five replicates, ± SE, .