Tanshinone IIA Attenuates Renal Fibrosis after Acute Kidney Injury in a Mouse Model through Inhibition of Fibrocytes Recruitment

Figure 1

Tanshinone IIA ameliorates renal dysfunction in mice with folic acid induced acute kidney injury. Graphs show the time course of BUN and serum creatinine levels at day 3 (a, d), day 14 (b, e), and day 28 (c, f) among different groups (). Data are expressed as the mean ± SEM. ^★ versus group TS; ^★★ versus group FA. Notes: blood urea nitrogen (BUN). Ctrl: mice treated with vehicle alone; TS: mice treated with Tanshinone IIA alone; FA: folic acid-treated mice followed by vehicle treatment; FA + TS: folic acid-treated mice subjected to Tanshinone IIA injection for 3 consecutive days.

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