Research Article

Survival of Mexican Children with Acute Myeloid Leukaemia Who Received Early Intensification Chemotherapy and an Autologous Transplant

Table 1

General and clinical characteristics of the paediatric patients with acute myeloid leukaemia.

CharacteristicPatients
Group A with EIaGroup B without EI
( = 20)( = 20)

Age (years)0.718
 Median (min–max)9 (2–15)9.5 (2–15)
Sex0.525
 Male11 (55%)11 (55%)
 Female9 (45%)9 (45%)
Leukocyte count (103/L)0.698
 Median28 25026 900
 Minimum–maximum9 700–125 0005 800–154 700
Morphological subtype (FABb)0.941
 M0, M1, M26 (30%)4 (20%)
 M31 (5%)1 (5%)
 M4, M511 (55%)12 (60%)
 M61 (5%)1 (5%)
 M71 (5%)2 (10%)
Karyotype0.900
 Normal8 (40%)6 (30%)
 t(8:21)aml/atg8 2 (10%)3 (15%)
 t(15:4)q+ 0 (0%)1 (5%)
 t(9:22)abr/bcl1 (5%)1 (5%)
 t(9:11)p22,q231 (5%)1 (5%)
 No data8 (40%)8 (40%)
Risk (by karyotype)0.870
 Normal4 (17%)3 (13%)
 Intermediate8 (33%)6 (25%)
 High2 (8%)1 (4%)
Risk (BFMc)0.669
 Low3 (15%)3 (15%)
 High17 (85%)17 (85%)

EI: early intensification.
bFAB: French-American-British classification.
cBFM: Berlin-Frankfurt-Münster study [39].