Research Article
Survival of Mexican Children with Acute Myeloid Leukaemia Who Received Early Intensification Chemotherapy and an Autologous Transplant
Table 1
General and clinical characteristics of the paediatric patients with acute myeloid leukaemia.
| Characteristic | Patients | | Group A with EIa | Group B without EI | ( = 20) | ( = 20) |
| Age (years) | | | 0.718 | Median (min–max) | 9 (2–15) | 9.5 (2–15) | | Sex | | | 0.525 | Male | 11 (55%) | 11 (55%) | | Female | 9 (45%) | 9 (45%) | | Leukocyte count (103/L) | | | 0.698 | Median | 28 250 | 26 900 | | Minimum–maximum | 9 700–125 000 | 5 800–154 700 | | Morphological subtype (FABb) | | | 0.941 | M0, M1, M2 | 6 (30%) | 4 (20%) | | M3 | 1 (5%) | 1 (5%) | | M4, M5 | 11 (55%) | 12 (60%) | | M6 | 1 (5%) | 1 (5%) | | M7 | 1 (5%) | 2 (10%) | | Karyotype | | | 0.900 | Normal | 8 (40%) | 6 (30%) | | t(8:21)aml/atg8 | 2 (10%) | 3 (15%) | | t(15:4)q+ | 0 (0%) | 1 (5%) | | t(9:22)abr/bcl | 1 (5%) | 1 (5%) | | t(9:11)p22,q23 | 1 (5%) | 1 (5%) | | No data | 8 (40%) | 8 (40%) | | Risk (by karyotype) | | | 0.870 | Normal | 4 (17%) | 3 (13%) | | Intermediate | 8 (33%) | 6 (25%) | | High | 2 (8%) | 1 (4%) | | Risk (BFMc) | | | 0.669 | Low | 3 (15%) | 3 (15%) | | High | 17 (85%) | 17 (85%) | |
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EI: early intensification.
bFAB: French-American-British classification.
cBFM: Berlin-Frankfurt-Münster study [39].
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