Research Article

Survival of Mexican Children with Acute Myeloid Leukaemia Who Received Early Intensification Chemotherapy and an Autologous Transplant

Table 2

Outcomes for paediatric patients with acute myeloid leukaemia, treated with early intensification chemotherapy or not.

ParameterPatients
Group A with EIaGroup B without EI
( = 20)( = 20)

CCRb18 (90%)12 (60%)0.028
Relapse
 Pretransplant1 (5%)0 (0%)
 Posttransplant1 (5%)8 (40%)0.031
Site of relapse
 BMc2 (10%)6 (30%)0.030
 CNSd0 (0%)1 (5%)
 BM + CNS0 (0%)1 (5%)
Current state
 Alive with CCR18 (90%)12 (60%)0.028
 Dead2 (10%)8 (40%)0.031
Cause of death
 Leukaemic activity2 (100%)8 (100%)0.031
 Related to APBTe0 (0%)0 (0%)

aEI: early intensification.
bCCR: continued complete remission.
cBM: bone marrow.
dCNS: central nervous system.
eAPBT: autologous peripheral blood transplant.