Comparison of Monkeypox Virus Clade Kinetics and Pathology within the Prairie Dog Animal Model Using a Serial Sacrifice Study Design

Figure 6

Histopathologic and immunohistochemical findings in a prairie dog that succumbed to West African MPXV (PD21). (a) Liver showing typical intracytoplasmic basophilic inclusions (arrows) by H&E staining and (b) multifocal staining of Orthopoxvirus antigens in hepatocytes by IHC. (c–e) Extensive staining of Orthopoxvirus antigens in spleen (c), salivary gland (d), and lung (e).

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