Polymorphism of 41 kD Flagellin Gene and Its Human B-Cell Epitope in Borrelia burgdorferi Strains of China

Table 4

Amino acid changes of the B-cell epitopes included in 41 kD flagellin antigen.

IEDB-ID	Epitopes	Base change
26607	IINHNTSAINASRNNGINAANLSKTQEKLSSGYRIN	GGC(G)-GCC(A)
27732	INRIADQAQY	No change
27733	INRIADQAQYNQMHMLSNKSASQNVRTAEELGMQPAKI	TCT(S)-GCT(A), AGA(R)-AAA(K)
54118	RIADQAQYNQ	No change
752	ADQAQYNQMH	No change
50350	QAQYNQMHML	No change
53012	QYNQMHMLSN	No change
45589	NQMHMLSNKS	No change
41667	MHMLSNKSAS	TCT(S)-GCT(A)
42062	MLSNKSASQN	TCT(S)-GCT(A)
59856	SNKSASQNVR	TCT(S)-GCT(A), AGA(R)-AAA(K)
7895	DEAIAVNIYAANVANLFSGEGAQTAQAAPVQEGVQQE	GCA(A)-TCA(S), TCT(S)-GCT(A),; ACT(T)-G(T)CT(AS), GCT(A)-ACT(T); GAG(E)-GAC(D), GTT(V)-GCT(A); CAG(Q)-GAG(E)
35977	LFSGEGAQTAQAAPVQEGVQQEGAQQPAPATAPSQGGVNSPVNVT	TCT(S)-GCT(A), ACT(T)-G(T)CT(A S)GCT(A)-ACT(T), GAG(E)-GAC(D),; GTT(V)-GCT(A), CAG(Q)-GAG(E),; GCA(A)-ACA(T), TCT(S)-ACT(T)
3341	ANLFSGEGAQTAQ	TCT(S)-GCT(A), ACT(T)-G(T)CT(A S)
58007	SGEGAQTAQAAPV	TCT(S)-GCT(A), ACT(T)-G(T)CT(A S),; GCT(A)-ACT(T)
52474	QTAQAAPVQEGVQ	ACT(T)-G(T)CT(A S), GCT(A)-ACT(T); GAG(E)-GAC(D), GTT(V)-GCT(A)
62967	TAQAAPVQEG	ACT(T)-G(T)CT(A S), GCT(A)-ACT(T); GAG(E)-GAC(D)
62968	TAQAAPVQEGVQQEGAQQPAPA	ACT(T)-G(T)CT(A S), GCT(A)-ACT(T); GAG(E)-GAC(D), GTT(V)-GCT(A); CAG(Q)-GAG(E), GCA(A)-ACA(T)
50213	QAAPVQEGVQ	GCT(A)-ACT(T), GAG(E)-GAC(D); GTT(V)-GCT(A)
379	AAPVQEGVQQEGA	GCT(A)-ACT(T), GAG(E)-GAC(D); GTT(V)-GCT(A), CAG(Q)-GAG(E)
3893	APVQEGVQQE	GAG(E)-GAC(D), GTT(V)-GCT(A); CAG(Q)-GAG(E)
70549	VQEGVQQEGA	GAG(E)-GAC(D), GTT(V)-GCT(A); CAG(Q)-GAG(E)
70550	VQEGVQQEGAQQP	GAG(E)-GAC(D), GTT(V)-GCT(A); CAG(Q)-GAG(E)
50610	QEGVQQEGAQQPAP	GAG(E)-GAC(D), GTT(V)-GCT(A); CAG(Q)-GAG(E), GCA(A)-ACA(T)
12306	EGVQQEGAQQ	GAG(E)-GAC(D), GTT(V)-GCT(A),; CAG(Q)-GAG(E)
12307	EGVQQEGAQQPA	GAG(E)-GAC(D), GTT(V)-GCT(A); CAG(Q)-GAG(E), GCA(A)-ACA(T)
70628	VQQEGAQQPA	GTT(V)-GCT(A), CAG(Q)-GAG(E),; GCA(A)-ACA(T)
52010	QQEGAQQPAPATA	CAG(Q)-GAG(E), GCA(A)-ACA(T)
50597	QEGAQQPAPA	CAG(Q)-GAG(E), GCA(A)-ACA(T)
51693	QPAPATAPSQGGV	GCA(A)-ACA(T), TCT(S)-ACT(T)
3820	APSQGGVNSPVNV	TCT(S)-ACT(T)
3821	APSQGGVNSPVNVTTTVDANTSLAKIENAIRMISDQRANLGAFQNR	TCT(S)-ACT(T), ATA(I)-GTG(V)
25890	IENAIRMISD	ATA(I)-GTG(V)
43169	NAIRMISDQR	ATA(I)-GTG(V)
28340	IRMISDQRAN	ATA(I)-GTG(V)
41672	MISDQRANLG	ATA(I)-GTG(V)
57265	SDQRANLGAF	No change
52186	QRANLGAFQN	No change
3342	ANLGAFQNRL	No change
36055	LGAFQNRLES	No change
1379	AFQNRLESIK	No change
65265	TMTDEVVAATTNSILTQSAMAMIAQANQVPQYVLSLLR	No change

Note: letters in bold font in the table represent the mutated amino acids in epitopes.