Evaluation of Bone Metabolism in Critically Ill Patients Using CTx and PINP

Table 1

Demographics, admission diagnosis, and characteristics of the patients (n = 28).

Variable	Values
Age, (range) yrs	67,4 ± 2,1 (45–88)
Male, n, %	16, (57,1)
Admission diagnosis, n
Pulmonary Infection, RR	15
Pulmonary edema, CHF	5
Complicated surgery	4
SAH/ICH	2
Abdominal sepsis	1
Trauma, head injury	1
Type, n
Medical	24
Surgical	4
APACHE II	22,2 ± 0,9
Predicted death rate, %	43,1
SOFA	10,1 ± 0,6
Outcome (mortality %)	10/28 (35,7)
MV duration, days	24,5 ± 5,1
ICU LOS (median), days	31,6 ± 5,7 (21)
Fever, >38.2°C	12/28
Low-dose steroids, n	17/28
Shock, nor-adrenaline, n	27/28
LMWH, n	17/28
Fondaparinux (Arixtra), n	9/28
Transfusions, n, (mean)	18/28 (2,9 ± 0,7 units)
Phenytoin (Epanutin), n	3/28
Albumin, g/dL	3,1 ± 0,1 (3,7–5,2)
Corrected calcium, mg/dL	8,2 ± 0,3 (8,5–10,5)
Phosphorus, mg/dL	3,4 ± 0,2 (2,5–4,8)
Alkaline phosphatase, U/L	120,0 ± 1,4 (42–141)
Urea, mg/dL	53,9 ± 5,3 (10–50)
AST (SGOT), IU/dL	44,4 ± 9,8 (9–36)
ALT (SGPT), IU/dL	68,9 ± 28,9 (20–28)
WBC, /mm^3	11,087 ± 1,415
Creatinine, mg/dL	1,1 ± 0.7 (0,6–1,4)
CRP, mg/dL	108,4 ± 20,1 (<3,16)
Food supplementation, n
Enteral	28/28
Parenteral	2
Both	2/28
Micronutrients	28/28
Vitamins	28/28

In parenthesis data represents range, n, percentages, or normal values. RR: respiratory failure, ICH: intracerebral hemorrhage, SAH: subarachnoid hemorrhage, CHF: congestive heart failure, LMWH: low molecular weight heparin, CRP: c-reactive protein, ICU: intensive care medicine, WBC: white blood cell, APACHE II: Acute Physiology And Chronic Health Evaluation, SOFA: Sequential Organ Failure Assessment, AST: Aspartate Aminotransferase, and ALT: Alanine Aminotransferase.