Antipsychotic Drugs Inhibit Platelet Aggregation via P2Y₁ and P2Y₁₂ Receptors

Figure 1

The effect of APDs on ADP-induced platelet aggregation in human platelets. PRPs were preincubated with 1 × 10⁻⁶ M (a) or indicated concentration (b) of APDs before stimulation with 10 μM ADP. This is a representative graph illustrating the aggregometer readings from one of three independent experiments (a). Experimental results are summarized as mean (±SD) percentage of aggregation in PRP (b). .

(a)

(b)