The Influence of Bone Marrow-Secreted IL-10 in a Mouse Model of Cerulein-Induced Pancreatic Fibrosis

Figure 3

Histology of the pancreas from cerulein treated female mice that received either wild-type or IL-10 knocked out male bone marrow transplants. The development of mild acute pancreatic inflammation from 1-day cerulein treated mice ((a) and (b), 200x). Acinar atrophy, architectural changes, and pseudotubular complexes were found in mice receiving cerulein for 3 and 6 weeks and persisted for a further 3 weeks after cerulein injections ((c)–(h), 200x).

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