Evaluation of Hepatotoxicity with Treatment Doses of Flucytosine and Amphotericin B for Invasive Fungal Infections

<div>The effect of flucytosine and amphotericin B coadministration on histological changes in the livers of experimental mice: (A) control group; (B) 50 mg/kg flucytosine + 300 <i>μ</i>g/kg amphotericin B group; (C) 100 mg/kg flucytosine + 600 <i>μ</i>g/kg amphotericin B group; (D) 150 mg/kg flucytosine + 900 <i>μ</i>g/kg amphotericin B group. CV: centrilobular vein; arrow: inflammatory cell infiltration.</div>

BioMed Research International

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Figure 1

Figure 1: Evaluation of Hepatotoxicity with Treatment Doses of Flucytosine and Amphotericin B for Invasive Fungal Infections 