Skeletal Muscle Remodelling as a Function of Disease Progression in Amyotrophic Lateral Sclerosis

Figure 6

Cell cycle regulation and muscle specific microRNAs in ALS patients. (a) Expression of miR-1, miR-133a, miR-206, and miR-455 in ALS patients compared to controls. (b–e) mRNA transcript in ALS during disease progression compared to controls for (b) p21, (c) p27, (d) SMAD3, and (e) IGF-1. for ALS samples and for controls. Asterisks indicate significant differences from controls; , , and .

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