Research Article

rLj-RGD3, a Novel Three-RGD-Motif-Containing Recombinant Protein from Lampetra japonica, Protects PC12 Cells from Injury Induced by Oxygen-Glucose Deprivation and Reperfusion

Figure 6

The effect of rLj-RGD3 on PC12 cell apoptosis after OGD-R injury as indicated by AO/EB fluorescence. (a), (b), (c), (d), (e), and (f) represented the control, model, rLj-RGD3 16, 8, and 4 μmol/L dose groups, and edaravone control group, respectively. Most PC12 cells were apoptotic after OGD-R. In contrast, apoptosis of the PC12 cells was significantly reduced in the rLj-RGD3 high-dose group.
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