Effect of Cigarette Smoke on Wound Healing of the Septal Mucosa of the Rat

Figure 6

Photomicrographs of the rat septal mucosa, 28 and 42 days after injury, with or without cigarette smoke exposure. (a) Experimental group: nasal mucosa hyperplasia, possible prepolypoid changes (long and short arrow), and goblet cell proliferation () after 28 days of cigarette smoke exposure. (b) Control group: minimal nasal epithelium squamous metaplasia, 28 days after injury. (c) Epithelial thickness with goblet cell proliferation and important obstruction (), after 42 days of cigarette smoke exposure. (d) Squamous metaplasia in the control group, 42 days after injury (hematoxylin and eosin stain; original magnification ×100, ×200).

(a)

(b)

(c)

(d)