Research Article

Potential Role of the Last Half Repeat in TAL Effectors Revealed by a Molecular Simulation Study

Figure 1

Complex structure and domain organization of AvrBs3 bound to DNA. (a) The complex structure of AvrBs3-DNA. In the crystal structure, AvrBs3 (yellow) contains a 17.5-repeat domain to mediate the DNA (red) binding. The unresolved last half repeat R17.5 was modeled based on the last half repeat in the dHax3-DNA structure (PDB codes: 3V6T) and was colored in blue separately. (b) The 17.5-repeat domain of AvrBs3 conferring DNA sequence. In each repeat, RVD residues are responsible for the specific nucleotide recognition of the DNA sense strand.
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