Research Article

Correlation-Based Network Generation, Visualization, and Analysis as a Powerful Tool in Biological Studies: A Case Study in Cancer Cell Metabolism

Table 3

The properties of the network of unique interactions under hypoxia conditions in the descending order according to betweenness centrality. The compound class 1 represents amino acids, 2 sugars and sugar alcohols, and 3 carboxylic acids.

MetaboliteCompound classDegreeBetweenness centrality

Ala1150.147
Creatinine1160.133
2OG3160.127
Tyr1130.113
Citrate3140.103
Pyruvate3110.060
Xylitol2110.037
Fructose270.033
Threitol260.010
Glycerol280.006
Asp180.005
Glucose270.004
Met160.004
Glu170.003
Myo-inositol270.003
Lys140.001
Putrescine130.001
GABA110.000
Gly110.000
Leu120.000
Malate330.000
Thr120.000