Clinical Study

The Efficacy of Infliximab Monotherapy versus Infliximab-Azathioprine Sequential Treatment in Crohn’s Disease: Experience from a Tertiary Medical Center in China

Table 1

Baseline characteristics of our study.

Variables IFX monotherapy group ()IFX-AZA sequential therapy group ()All () value

Male sex, (%)16 (72.7)38 (66.7)54 (68.4)0.604
Duration of symptoms (week)0.733
Age of onset (yr)0.217
Location of lesions, (%)0.829
 Ileum6 (27.3)20 (35.1)26 (32.9)
 Colon3 (13.6)6 (10.5)9 (11.4)
 Ileocolon12 (54.5)30 (52.6)42 (53.2)
 Upper GI tract1 (4.5)1 (1.8)2 (2.5)
Behavior of disease, (%)0.252
 Nonstenosis, nonfistula14 (63.6)46 (80.7)60 (75.9)
 Stenosis4 (18.2)7 (12.3)11 (13.9)
 Fistula4 (18.2)4 (7.0)8 (10.1)
Perianal disease, (%)9 (40.9)20 (35.1)29 (36.7)0.630
CDAI0.457
CDEIS0.964
Deep remission at week 3013 (59.1)31 (54.4)44 (55.7)0.706
Complete endoscopic remission at week 3013 (59.1)31 (54.4)44 (55.7)0.706
Endoscopic remission at week 3019 (86.4)42 (73.7)61 (77.2)0.365
Endoscopic improvement at week 3021 (95.5)54 (94.7)75 (94.9)0.999