BioMed Research International

Research Article

Basic Parameters of Blood Count as Prognostic Factors for Renal Cell Carcinoma

Table 2

Univariate Cox regression. Statistically significant parameters predictive of metastasis, recurrence, and death specifically due to renal cell carcinoma.


AD	AP	Regression coefficient	SE	HR	value	N	Number of events

Metastasis	NSS/NF	1,550	0,744	4,710	0,0370	230	21
	Tumor location C (ref.)	0,000		1,000		230	21
	Location L	−2,340	0,764	0,096	0,0022
	Location U	−2,470	0,817	0,084	0,0025
	Location D	−1,750	0,652	0,174	0,0073
	T	0,525	0,141	1,690	0,0002	230	21
	PLT [thousand/μL]	0,005	0,002	1,010	0,0030	230	21

Recurrence	Tumor size (cm)	0,088	0,030	1,090	0,0027	230	25
	G	0,626	0,281	1,87	0,0260	230	25
	T	0,426	0,123	1,530	0,0005	230	25
	HGB [g/dL]	−0,397	0,102	0,672	0,0001	230	25
	HCT [%]	−0,121	0,052	0,886	0,0200	230	13
	MCV [fL]	−0,113	0,026	0,893	0,0000	230	25
	MCH [pg]	−0,196	0,065	0,822	0,0025	230	25
	PLT [thousand/μL]	0,008	0,001	1,010	0,0000	230	25

Death	NSS/NF	1,280	0,436	3,600	0,0033	230	49
	Tumor size (cm)	0,101	0,020	1,110	0,0000	230	49
	G	0,704	0,202	2,020	0,0005	230	49
	T	0,510	0,089	1,670	0,0000	230	49
	HGB [g/dL]	−0,356	0,077	0,700	0,0000	230	49
	HCT [%]	−0,114	0,038	0,892	0,0024	230	27
	MCV [fL]	−0,105	0,019	0,900	0,0000	230	49
	MCHC [g/dL]	−0,148	0,057	0,863	0,0098	230	49
	MCH [pg]	−0,206	0,049	0,814	0,0000	230	49
	RDW [%]	0,155	0,056	1,170	0,0056	230	49
	PLT [thousand/μL]	0,009	0,001	1,010	0,0000	230	49
	MPV [fL]	−0,375	0,093	0,687	0,0001	230	49

AE: adverse event; AP: analyzed parameters; HR: hazard ratio; SE: standard error; location C:central location of the tumor; location L: tumor in the lower pole of the kidney; location U: tumor in the upper pole of the kidney; location D: tumor in the dorsal part of the kidney; T: tumor scale; G: Fuhrman scale; PLT: platelets count; HGB: hemoglobin level; HCT: hematocrit; MCV: mean corpuscular volume; MCHC: mean corpuscular hemoglobin concentration; MCH: mean corpuscular hemoglobin; RDW: red blood cell distribution width; MPV: mean platelet volume; NSS: nephron sparing surgery; NF: nephrectomy.