Research Article

Thrombin Maybe Plays an Important Role in MK Differentiation into Platelets

Figure 2

Thrombin promotes the appearance of pseudopodia in Meg-01 cells. After treatment with TPO (80 ng/mL) or thrombin (2 U/mL) for 24 h, cells developed pseudopodia (indicated by arrows). Meanwhile, cells cultured in medium with no treatment (negative control) did not show this phenomenon. Cells cultured in medium containing 10% FBS stuck together. Similar results were observed in two additional experiments.