Review Article

Genetic Association of CHAT rs3810950 and rs2177369 Polymorphisms with the Risk of Alzheimer’s Disease: A Meta-Analysis

Table 2

Quality assessment scheme for the included literatures (Newcastle-Ottawa Scale).

First authorYearSelectionComparabilityExposureTotal
IIIIIIIVVVIVIIVIII

Mubumbila [13]2002
Harold [20]2003
Kim [12]2004
Cook [21]2005
Ahn Jo [14]2006
Ozturk [15] 2006
Tang [16]2008
Grünblatt [17]2009
Grünblatt [18]2011
Mengel-From [10]2011
Lee [19]2012
Piccardi [22]2007
Scacchi [23] 2009

Note: I: is the case definition adequate? II: representativeness of the cases. III: selection of controls. IV: definition of controls. V: comparability of cases and controls on the basis of the design or analysis. VI: ascertainment of exposure. VII: same method of ascertainment for cases and controls. VIII: nonresponse rate.