Research Article
Oral Candida in Patients with Fixed Orthodontic Appliance: In Vitro Combination Therapy
Table 1
Pharmacodynamic data of candida isolated from patients with fixed orthodontic appliance. MIC: minimal inhibitory concentration (mg/L); AMB: amphotericin B; KET: ketoconazole; ITR: itraconazole.
| | Candidal isolates | Associated bacteria | MIC for AMB | MIC for KET | MIC for ITR |
| | C. albicans (1) | S. viridans | 0.5 | 1.0 | 1.0 | | C. albicans (2) | S. viridans | 0.5 | 1.0 | 1.0 | | C. albicans (3) | S. viridans | 0.5 | 1.0 | 1.0 | | C. albicans (4) | S. viridans | 0.5 | 1.0 | 1.0 | | C. albicans (5) | P. aeruginosa,
S. viridans | 0.5 | 2.0 | 2.0 | | C. albicans (6) | P. aeruginosa | 0.5 | 2.0 | 1.0 | | C. albicans (7) | P. aeruginosa | 0.5 | 2.0 | 1.0 | | C. albicans (8) | E. coli,
S. viridans | 0.5 | 2.0 | 2.0 | | C. albicans (9) | E. coli | 0.5 | 1.0 | 1.0 | | C. albicans (10) | E. coli | 0.5 | 1.0 | 2.0 | | C. dubliniensis (1) | S. viridans | 0.5 | 1.0 | 1.0 | | C. dubliniensis (2) | S. viridans | 0.5 | 2.0 | 1.0 | | C. dubliniensis (3) | E. coli | 0.5 | 2.0 | 2.0 | | C. parapsilosis (1) | S. viridans | 0.5 | 1.0 | 1.0 | | C. parapsilosis (2) | S. aureus, S. viridans | 1.0 | 1.0 | 1.0 | | C. krusei | P. aeruginosa | 0.5 | 4.0 | 2.0 | | C. glabrata | S. viridans | 0.25 | 1.0 | 1.0 | | C. tropicalis | S. viridans | 0.25 | 1.0 | 1.0 |
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