IFN-τ Displays Anti-Inflammatory Effects on Staphylococcus aureus Endometritis via Inhibiting the Activation of the NF-κB and MAPK Pathways in Mice

Figure 5

Effects of IFN-τ on TLR2. (a) The TLR2 mRNA levels in the uterine tissues. (b) The TLR2 and IL-8 protein levels in HEK293-mTLR2 cells. qPCR was performed to assess the mRNA levels of TLR2. Western blotting was performed to detect the protein levels of TLR2. β-Actin was used as a control. The CG refers to the control group, S. aureus refers to the mice with S. aureus-induced endometritis that were not given any drug treatment, 8, 4, and 2 refer to the IFN-τ (2, 4, and 8 mg/kg) administration groups, and DEX refers to the dexamethasone treatment group. , significantly different from the CG; ^#, significantly different from the S. aureus group.

(a)

(b)