Genetic Variants in the Promoter Region of miR-10b and the Risk of Breast Cancer

Table 3

Annotation of variants with strong linkage disequilibrium with the SNP rs4078756 in HaploRegV4.1.

Chr	Pos; (hg19)	LD; ()	Variant	Ref	Alt	ASN freq	Promoter histone marks	DNAse	Proteins bound	Motifs changed
2	177000616	1.00	rs1348808	T	C	0.23	15 tissues	12 tissues	CTBP2	Ets, LF-A1, NF-E2
2	177001145	1.00	rs76652183	G	T	0.23	19 tissues	18 tissues	5 bound proteins	EBF
2	177001378	1.00	rs3731795	A	G	0.27	19 tissues	7 tissues		CTCF, p300
2	177001962	0.96	rs79025511	C	T	0.23	19 tissues	MUS, MUS		Gcm1
2	177004689	0.92	rs72927149	G	C	0.23	12 tissues	6 tissues		Pax-5
2	177005519	1.00	rs79120932	G	T	0.23	19 tissues	32 tissues	5 bound proteins	4 altered motifs
2	177007102	1.00	rs67435554	G	T	0.23
2	177007527	1.00	rs76363873	A	G	0.23	IPSC			GATA, MZF1::1–4
2	177008484	1.00	rs79440139	T	A	0.23				6 altered motifs

Chr: chromosome, Pos: position, LD: linkage disequilibrium in CHB + JPT population, Ref: reference, Alt: alternative, freq: frequency, MUS: musculus, and IPSC: induced pluripotent stem cell.