Stellate Cell Activation and Imbalanced Expression of TGF-β1/TGF-β3 in Acute Autoimmune Liver Lesions Induced by ConA in Mice

Table 2

Levels of serum TGF-β1 and TGF-β3 in mice after ConA injection.

	()	TGF-β1 (pg/mL)	TGF-β3 (pg/mL)	TGF-β3/β1 ratio
Control	8
2 h	7
8 h	5
24 h	7
48 h	8

8 h and 24 h after ConA injection, serum concentrations of TGF-β1 were significantly higher than the control group ( and 0.046, resp.); peak time was 8 h.
After ConA injection, on 8 h and 24 h, concentration of TGF-β3 was also significantly higher than the control group ( and 0.043, resp.); peak time was 8 h.
After ConA injection, the ratio of TGF-β3/TGF-β1 decreased significantly at 48 h compared with control group ().