HOXB9 Expression Correlates with Histological Grade and Prognosis in LSCC

Table 2

Correlation of HOXB9, HOXB13, and HOXD13 genes expression levels with clinicopathological variables in LSCC patients ().

Variable	Cases ()	HOXB9 expression		value	HOXB13 expression		value	HOXD13 expression		value
		High	Low		High	Low		High	Low
Age (years)
≤60	75	55	20	0.435	46	29	0.104	55	20	0.431
>60	93	73	20		68	25		63	30
Tumor location
Supraglottic	70	50	20	0.221	50	20	0.402	45	25	0.154
Glottic	98	78	20		6	34		73	25
Tumor size (cm)
<2.5	72	50	22	0.075	46	26	0.34	52	20	0.691
≥2.5	96	78	18		68	28		66	30
Pathological grade
Well/moderate	105	72	33		70	35	0.67	70	35	0.191
Poor	63	56	7		44	19		48	15
Lymphatic invasion
No	106	80	26	0.775	70	36	0.509	72	34	0.466
Yes	62	48	44		44	18		46	16
T classification
T1 + T2	101	76	25	0.725	72	29	0.243	70	31	0.746
T3 + T4	67	52	15		42	25		48	19
Clinical stage
I + II	98	72	26	0.327	65	33	0.615	68	30	0.776
III + IV	70	56	14		49	21		50	20

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