Markers of Alzheimer’s Disease in Primary Visual Cortex in Normal Aging in Mice

Figure 4

Double IF to detect glial fibrillary acidic protein (GFAP), an inflammation marker (green channel), in the VC of 4 M and 25 M old mice. 15 um thick brain tissue sections of VC from mice were used. DAPI stain for nuclei (DAPI) and Merge are shown. Observe GFAP overexpression and an increased number of astrocytes in the VC of 25 M old mice. Scale bar: 20 µm.