Prediction of Radix Astragali Immunomodulatory Effect of CD80 Expression from Chromatograms by Quantitative Pattern-Activity Relationship

Table 1

The immunomodulatory effect (relative change of CD80 expression to the blank, %, after standardization) of each RA extract from three batches on THP-1 cell.

Batch A		Batch B		Batch C
Sample	Act. activity (%)	Sample	Act. activity (%)	Sample	Act. activity (%)
A1	+12.70	B1	+1.87	C1	+15.58
A2	+8.33	B2	−2.25	C2	+20.29
A3	+15.48	B3	+2.25	C3	+20.29
A4	+14.68	B4	+17.23	C4	+43.48
A5	+15.08	B5	+8.61	C5	+35.14
A6	+9.52	B6	−4.87	C6	+26.45
A7	+15.08	B7	+20.60	C7	+22.46
A8	+5.95	B8	−7.12	C8	+57.25
A9	+7.54	B9	+16.10	C9	+25.36
A10	0	B10	−1.12	C10	+25.36
A11	0	B11	−4.12	C11	+29.35
A12	+2.38	B12	−8.24	C12	+27.17
A13	+0.79	B13	−15.36	C13	+27.54
A14	+2.78	B14	−10.11	C14	+19.20
A15	0	B15	−7.87	C15	+27.17
A16	+3.57	B16	−7.12	C16	+26.81
A17	−10.32	B17	−7.49	C17	+21.38
A18	−8.73	B18	−8.24	C18	+19.20
A19	−6.35	B19	−4.87	C19	+19.20
A20	−14.68	B20	−12.36	C20	+19.93
A21	+25.00	B21	−11.75	C21	+17.17
A22	+13.86	B22	−17.17	C22	+5.12
A23	+30.72	B23	−19.28	C23	+2.41
A24	+6.02	B24	−17.47	C24	−7.23
Avg +6.23		Avg −4.17		Avg +22.75
SD 10.75		SD 10.78		SD 12.66
Max +30.72		Max +20.60		Max +57.25
Min −14.68		Min −19.28		Min −7.23