Effect of R119G Mutation on Human P5CR1 Dynamic Property and Enzymatic Activity

Figure 1

Superimposed 3D structures of WT (blue) and R119G mutant (pale green) P5CR. Changes in the protein stability upon R119G mutation predicted by Foldx. values are changes in the protein unfolding free energy after R119G mutation. ΔΔG < 0: increased stability; ΔΔG > 0: decreased stability.

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