A New Platelet-Aggregation-Inhibiting Factor Isolated from Bothrops moojeni Snake Venom

Figure 3

Effect of BmooPAi from B. moojeni venom on (a) ristocetin-, (b) ADP-, and (c) collagen-induced platelet aggregation. Aggregation was triggered with the agonists immediately after adding the indicated doses of BmooPAi to citrated human PRP at 37°C. Platelet aggregation was recorded for 10 min in an AggRAM platelet aggregation system with four-channel laser optics (Helena Laboratories, EUA). Results are expressed as an increase in light transmission, where PPP represents the maximum response (100%). Control experiments were performed in the absence of BmooPAi.

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