Study Publication year Country Sample size Mean age (yrs) Percentage male (%) History of stroke (%) History of DM (%) History of CVD (%) Reported outcomes Follow-up periods (yrs) Adjusted factors NOS score Khachaturian et al. [19 ] 2006 USA 11.2 11.1 AD Age, sex, education, APOE ε 4 alleles, DM, cholesterol, MI, and stroke In’t Veld et al. [12 ] 2001 Netherlands 10.0 NA Any dementia, AD, VD, CI, and CD Age, gender, DBP and SBP, DM, stroke, BMI, baseline MMSE, smoking, education, living situation, and PAD Stewart et al. [14 ] 2009 USA 32.0 NA Any dementia, AD Age Luchsinger et al. [20 ] 2005 USA NA 20.3 28.9 AD Age, gender, education, APOE-ɛ4 allele, and ethnicity Qiu et al. [15 ] 2004 Sweden NA NA NA Any dementia, AD, and CI Age, sex, education, MMSE score, vascular morbidity, functional dependence, and APOE ε 4 alleles Bruce et al. [16 ] 2008 Australia 100.0 36.1 Any dementia Crude Tully et al. [13 ] 2016 France 14.2 10.6 Any dementia Sex, center, education, BMI, stroke, hypercholesterolemia, DM, center, CKD, APOE-ɛ4, SBP, and DBP Solfrizzi et al. [21 ] 2013 Italy 11.6 17.0 CI Age, gender, education, smoking status, type 2 DM, CAD, serum creatinine level, apolipoprotein B to apolipoprotein A1 ratio, history of stroke, and hypertension Haring et al. [17 ] 2016 USA 65–79 6.6 16.5 Any dementia, CI, and CD Age, race, education, WHI menopausal hormone therapy arm, baseline 3MSE, alcohol, smoking status, physical activity, DM, BMI, depression, total energy intake, and history of CVD Yasar et al. [18 ] 2013 USA 9.0 9.9 AD Age, sex, education, income, CVD, BMI, SBP, DBP, and MCI
