Novel Mutations and Mutation Combinations of<i> TMPRSS3</i> Cause Various Phenotypes in One Chinese Family with Autosomal Recessive Hearing Impairment

<div>Molecular modeling of wild-type and mutant TMPRSS3. (a) The mutant protein Thr306 is predicted to have three hydrogen bonds and add one hydrogen bond compared to the wild-type protein. (b) Arg106 lies within a loop. The wild-type protein has a longer side chain than the mutant protein.</div>

BioMed Research International

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Figure 5

Figure 5: Novel Mutations and Mutation Combinations of<i> TMPRSS3</i> Cause Various Phenotypes in One Chinese Family with Autosomal Recessive Hearing Impairment 

Figure 5 | Novel Mutations and Mutation Combinations of TMPRSS3 Cause Various Phenotypes in One Chinese Family with Autosomal Recessive Hearing Impairment 