Protective Effects of the Segmental Renal Artery Clamping Technique on Ischemia-Reperfusion Injury in db/db Diabetic Mice

Figure 7

Nonischemic area expresses less KIM-1 and TNF-α mRNA. Kim-1 (a) and TNF-α (b) mRNA expression were measured by RT-PCR and were calculated. KIM-1 and TNF-α mRNA in renal tissues rise markedly after the surgery except the mice in sham group. However, expression of KIM-1 and TNF-α mRNA in nonischemic area (SRAC group) was much lower than ischemic area (SRAC group) and RAC group (). Overall expression of KIM-1 and TNF-α mRNA in GSE(−) group was higher than GSE(+) group but this difference failed to achieve statistical significance. Data are mean ± SEM; .

(a)

(b)