Research Article

In Vitro Screening of Three Indian Medicinal Plants for Their Phytochemicals, Anticholinesterase, Antiglucosidase, Antioxidant, and Neuroprotective Effects

Table 3

IC50 values of 90% methanolic extracts and their derived fractions from titled plants for AChE, BuChE, and α-Glc inhibition assays.

PlantExtractIC50 values (µg/mL)
AChEBuChEα-Glc

A. alnifolia90% MeOH59.22 ± 2.1541.74 ± 1.2745.24 ± 4.01
CHCl332.88 ± 3.00633.62 ± 2.8341.86 ± 1.31
-BuOH257.47 ± 11.89144.27 ± 12.56264.41 ± 29.9
H2O64.8 ± 3.2261.6 ± 5.3286.4 ± 19.99

P. indica90% MeOH17.77 ± 3.1720.22 ± 2.842.76 ± 2.0
CHCl352.09 ± 2.538.97 ± 8.135.29 ± 1.6
-BuOH60.12 ± 0.8474.67 ± 2.792.99 ± 2.8
H2O100.37 ± 1.99355.95 ± 4.750.27 ± 2.3

O. obtusata90% MeOH82.16 ± 2.5547.48 ± 18.2728.7 ± 1.9
CHCl325.7 ± 0.319.83 ± 1.2839.3 ± 1.6
-BuOH174.38 ± 27.005233.28 ± 13.2687.07 ± 4.9
H2O369.15 ± 8.6332.28 ± 18.1797.35 ± 9.7

Galantamine0.77 ± 0.098.1 ± 0.02

Acarbose117.20 ± 0.017