Identification of Significant Pathways Induced by PAX5 Haploinsufficiency Based on Protein-Protein Interaction Networks and Cluster Analysis in Raji Cell Line

Table 1

Functional annotation clustering in the DAVID disease/cancer database.

Cluster	Count	Score	Genes
Gene transcription	17	2.31	HIST2H3A, HIST1H2BC, HIST1H2BF, HIST1H2AD, HIST1H3B, HIST1H4E, HIST1H3D, HIST1H4C, HIST1H2AM, HIST1H4I, HIST1H2AL, HIST2H3C, EGFR, FOS, CALR, EYA1, MAGI1
Inflammatory and immune response	6	1.42	TICAM2, CCL4L2, TLR4, FOS, AKT3, PTPN6
Pathways in cancer	7	1.39	EGFR, CCNE1, FOS, MMP9, FGF12, AKT3, CTNNA3
Cell adhesion	7	1.38	EGFR, CNTNAP4, MAGI1, CTNND1, CCL4L2, CTNNA3, PTPN6
Protein phosphatase	7	1.34	EGFR, PTPN6, EYA1, PTPRG, ROR1, AKT3, CDK3
Tight junction	4	1.03	EPB41L3, MAGI1, AKT3, CTNNA3