Ferulic Acid Suppresses Amyloid β Production in the Human Lens Epithelial Cell Stimulated with Hydrogen Peroxide

Figure 1

Effect of H₂O₂ stimulation on Aβ_1–40 (a), Aβ_1–42 (b), Aβ_1–43 (c), and cell viability (d) in HLE cells. The HLE cells were stimulated by 1–100 μM H₂O₂ for 24 h. Open columns (none) = unstimulated HLE cells. Closed columns = H₂O₂-stimulated HLE cells. N.D. = not detectable. The data are presented as the means ± SE of 5–8 experiments. , versus none for each category.

(a) Aβ_1–40 levels

(b) Aβ_1–42 levels

(c) Aβ_1–43 levels

(d) Cell viability