Ferulic Acid Suppresses Amyloid β Production in the Human Lens Epithelial Cell Stimulated with Hydrogen Peroxide

Figure 2

Effect of H₂O₂ stimulation on mRNA levels of APP (a), BACE1 (b), PS1 (c), PS2 (d), ADAM10 (e), NEP (f), and ECE1 (g) in HLE cells. The HLE cells were stimulated with 1–100 μM H₂O₂ for 24 h. Open columns (none) = unstimulated HLE cells. Closed columns = H₂O₂-stimulated HLE cells. The data are presented as the means ± SE of 5–8 experiments. , versus none for each category.

(a) APP mRNA

(b) BACE1 mRNA

(c) PS1 mRNA

(d) PS2 mRNA

(e) ADAM10 mRNA

(f) NEP mRNA

(g) ECE1 mRNA